Anti-Autophagy-related protein 9A ATG9A Antibody

Primary Antibodies

Boster Bio Anti-Autophagy-related protein 9A ATG9A Antibody (Catalog # A03757). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9A, a multi-spanning membrane protein localizing to the Golgi apparatus and late endosomes, has been proposed to mediate membrane transport to generate autophagosomes. ATG9A has also been implicated as a regulator of STING (stimulator of interferon genes)-mediated innate immune response.

Polyclonal

ATG9A Antibody is supplied in PBS containing 0.02% sodium azide.

ATG9A antibody can be used for detection of ATG9A by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

ATG9A Antibody is affinity chromatography purified via peptide column.

ATG9 autophagy related 9 homolog A (S. cerevisiae)

Involved in autophagy and cytoplasm to vacuole transport
(Cvt) vesicle formation. Plays a key role in the organization of
the preautophagosomal structure/phagophore assembly site (PAS),
the nucleating site for formation of the sequestering vesicle.
Cycles between a juxta-nuclear trans-Golgi network compartment and
late endosomes. Nutrient starvation induces accumulation on
autophagosomes. Starvation-dependent trafficking requires ULK1,
ATG13 and SUPT20H.

ATG9 autophagy related 9 homolog A (S. cerevisiae)