Item no. |
BOS-A00993-5-10ug |
Manufacturer |
Boster
|
Amount |
10ug |
Format |
Lyophilized |
Applications |
WB, FC, ELISA |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Short Description |
Boster Bio Anti-UPAR/Plaur Antibody Picoband™ catalog # A03740-1. Tested in WB, FCM(Intracellular), ELISA applications. This antibody reacts with Mouse, Rat. |
Description |
Boster Bio Anti-UPAR/Plaur Antibody Picoband™ catalog # A03740-1. Tested in WB, FCM(Intracellular), ELISA applications. This antibody reacts with Mouse, Rat. |
Background |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Gene Name |
PLAUR |
Application Details |
Western blot, 0.25-0.5 μg/ml, Mouse, Rat Flow Cytometry (Intracellular), 1-3 μg/1x106 cells, Rat ELISA, 0.1-0.5 μg/ml, Rat |
Application Notes |
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
Immunogen |
E.coli-derived rat UPAR/Plaur recombinant protein (Position: L25-R261). Rat Plaur shares 63.7% and 90.3% amino acid (aa) sequence identity with human and mouse Plaur, respectively. |
Purification |
Immunogen affinity purified. |
Storage |
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. |
Reconstitution |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Molecular Weight |
50 kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.