Comparison

Volasertib

Item no. RPE-CV-1045-2
Manufacturer rPeptide
Amount 25 mg
Category
Type Inhibitors
Format Powder
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Territory
This product is only available for customers from Austria or Switzerland!
Manufacturers Category
COVID-19/ Small Molecules
Storage
-20°C
Shipping
Ambient
Description (Long)
Volasertib is an extremely potent and selective inhibitor of Polo-like kinase, a critical controller of multiple essential steps of mitosis (IC50: Plk1=0.87 nM, Plk2=5 nM, Plk3=56 nM). It has shown efficacy in multiple solid xenograft tumors models1 and in clinical studies in patients with acute myeloid leukemia. Volasertib has also been shown to potently inhibit BRD4 (Kd=79 nM3, IC50’s bromodomains 1 and 2 of BRD4=300 and 770 nM respectively).
Physical State
Off-white powder

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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