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N,O-Didansyl-L-tyrosine (cyclohexylammonium)

N,O-Didansyl-L-tyrosine (cyclohexylammonium)

Item no.	HY-W142014-100mg
Manufacturer	MedChem Express
CASRN	102783-47-1
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Citations	[1]T A Fritz, et al. Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase. Chem Biol. 2001 Oct;8(10):981-95.
Smiles	NC1CCCCC1.O=S(OC(C=C2)=CC=C2C[C@@H](C(O)=O)NS(=O)(C3=CC=CC4=C3C=CC=C4N(C)C)=O)(C5=CC=CC6=C5C=CC=C6N(C)C)=O
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Product Description	N, O-Didansyl-L-tyrosine cyclohexylammonium is a potent selective thymidylate synthase (TS) inhibitor, acts on TS of Escherichia coli, Lactobacillus casei and human with the IC50 values of 5.0, 3.4 and 119 μM, respectively[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	746.94
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	Thymidylate Synthase
Manufacturers Target	Thymidylate Synthase
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Peptides

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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