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TLQP-21

TLQP-21

Item no.	HY-P1345-100mg
Manufacturer	MedChem Express
CASRN	869988-94-3
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Citations	[1]Elena Bresciani , et al. TLQP-21, A VGF-Derived Peptide Endowed of Endocrine and Extraendocrine Properties: Focus on In Vitro Calcium Signaling. Int J Mol Sci. 2019 Dec 24;21(1):130.<br/>[2]Cheryl Cero, et al. The TLQP-21 Peptide Activates the G-protein-coupled Receptor C3aR1 via a Folding-Upon-Binding Mechanism. ructure. 2014 Dec 2;22(12):1744-1753.
Smiles	C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@H](CC3=CN=CN3)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]6N(C(=O)[C@H]7N(C([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CC(C)C)=O)CCC(N)=O)=O)CCC7)CCC6)C)=O)CO)=O)CO)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)=O)=O)=O)C)=O)CC(C)C)=O)CCC1)N8[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)C)=O)CCC8
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Product Description	TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions[1][2].
Shipping	Room temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	2432.75
Clinical Information	No Development Reported
Manufacturers Research Area	Endocrinology; Neurological Disease
Solubility	H2O
Target	Complement System
Manufacturers Target	Complement System
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Peptides

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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