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PDZ1 Domain inhibitor peptide (TFA)

PDZ1 Domain inhibitor peptide (TFA)

Item no.	HY-P1195A-100mg
Manufacturer	MedChem Express
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Citations	[1]Andrea Piserchio, et al. Targeting specific PDZ domains of PSD-95; structural basis for enhanced affinity and enzymatic stability of a cyclic peptide. Chem Biol. 2004 Apr;11(4):469-73.
Smiles	O=C([C@H](CCCCN)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)N[C@@H]2C(N[C@@](C(N[C@@H](CCC(NCCCC2)=O)C(N[C@@H](C)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)([H])[C@H](O)C)=O.OC(C(F)(F)F)=O
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Product Description	PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain[1].
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	933.97
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	H2O
Target	iGluR
Manufacturers Target	iGluR
Manufacturers Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Peptides

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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