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GCKR Antibody (C-term) Blocking Peptide

GCKR Antibody (C-term) Blocking Peptide

Item no.	ABC-BP8143b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	GCKR, Glucokinase regulatory protein, GKRP, Glucokinase regulator
Available
Primary Accession	Q14397
Bio Background	GCKR belongs to the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. Th GCKR gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Bio References	Veiga-da-Cunha, M., et al., Diabetologia 46(5):704-711 (2003).Hayward, B.E., et al., Genomics 49(1):137-142 (1998).Hayward, B.E., et al., Mamm. Genome 7(6):454-458 (1996).Warner, J.P., et al., Mamm. Genome 6(8):532-536 (1995).Vaxillaire, M., et al., Diabetes 43(3):389-395 (1994).
Gene ID	2646
Gene Name	GCKR {ECO:0000303\|PubMed:8589523, ECO:0000312\|HGNC:HGNC:4196}
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP8143b was selected from the C-term region of human GCKR . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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