Item no. |
ABC-BP8009a |
Manufacturer |
Abcepta
|
Amount |
500 ug |
Category |
|
Type |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
RPS6KB2, STK14B, Ribosomal protein S6 kinase beta-2, 70 kDa ribosomal protein S6 kinase 2, S6 kinase-related kinase, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, SRK, p70 S6 kinase beta, S6K2, p70 S6KB, p70-beta, S6K-beta, S6K-beta-2, P70S6K2, p70-S6K 2, p70 S6K-beta |
Available |
|
Primary Accession |
Q9UBS0 |
Bio Background |
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK). |
Bio References |
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Lee-Fruman, K.K., et al., Oncogene 18(36):5108-5114 (1999).Saitoh, M., et al., Biochem. Biophys. Res. Commun. 253(2):470-476 (1998).Gout, I., et al., J. Biol. Chem. 273(46):30061-30064 (1998). |
Gene ID |
6199 |
Gene Name |
RPS6KB2 |
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence used to generate the antibody AP8009a was selected from the C-term region of human p70 S6Kbeta . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.