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MEK1/2 Antibdoy (S222) Blocking Peptide

MEK1/2 Antibdoy (S222) Blocking Peptide

Item no.	ABC-BP7904c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	MAP2K1, MEK1, Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAPK/ERK kinase 1, PRKMK1, MKK1, MAP kinase kinase 1, MAPKK 1, MEK 1
Available
Primary Accession	Q02750
Bio Background	MEK1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Bio References	Zheng, B., et al., Blood 102(3):1019-1027 (2003).Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003).Zhu, X., et al., J. Neurochem. 86(1):136-142 (2003).Fringer, J., et al., J. Biol. Chem. 278(23):20612-20617 (2003).Witowsky, J.A., et al., J. Biol. Chem. 278(3):1403-1406 (2003).
Gene ID	5604
Gene Name	MAP2K1 (HGNC:6840)
Subtitle	Synthetic peptide
Other Accession	P46734
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP7904c was selected from the S222 region of human MEK1/2 Antibdoy (S222). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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