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RAF1 Antibody (S494) Blocking Peptide

RAF1 Antibody (S494) Blocking Peptide

Item no.	ABC-BP7816c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	RAF1, Raf-1, RAF proto-oncogene serine/threonine-protein kinase, Proto-oncogene c-RAF, RAF, cRaf
Available
Primary Accession	P04049
Bio Background	RAF1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, RAF1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.
Bio References	Chong, H., et al., J. Biol. Chem. 278(38):36269-36276 (2003).Lee, M., et al., Cancer Lett. 193(1):57-64 (2003).Alavi, A., et al., Science 301(5629):94-96 (2003).Fringer, J., et al., J. Biol. Chem. 278(23):20612-20617 (2003).Oehrl, W., et al., J. Biol. Chem. 278(20):17819-17826 (2003).
Gene ID	5894
Gene Name	RAF1
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP7816c was selected from the S494 region of human RAF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/8/2024

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