Comparison

PHLPP2 Antibody (C-term) Blocking Peptide

Item no. ABC-BP7799b
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 5.1 34160400
ECLASS 6.1 34160400
ECLASS 8.0 32160409
ECLASS 9.0 32160409
ECLASS 10.0.1 32160409
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products PHLPP2, PHLPPL, KIAA0931, PH domain leucine-rich repeat-containing protein phosphatase 2, PHLPP-like, PH domain leucine-rich repeat-containing protein phosphatase-like
Available
Primary Accession
Q6ZVD8
Bio Background
PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.
Bio References
Brognard, J., Mol. Cell 25 (6), 917-931 (2007)
Gene ID
23035
Gene Name
PHLPP2
Subtitle
Synthetic peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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