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IMPDH2 Antibody (N-term) Blocking Peptide

IMPDH2 Antibody (N-term) Blocking Peptide

Item no.	ABC-BP7390a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	IMPD2, IMPDH-II, 111205 {ECO:0000255\|HAMAP-Rule:MF_03156}, Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMP dehydrogenase 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPD 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH 2 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH2 {ECO:0000255\|HAMAP-Rule:MF_03156}
Available
Primary Accession	P12268
Bio Background	IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Bio References	Sombogaard, F., Pharmacogenet. Genomics 19 (8), 626-634 (2009)Mohamed, M.F., Genet. Test. 12 (4), 513-516 (2008)
Gene ID	3615
Gene Name	IMPDH2 (HGNC:6053)
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP7390a was selected from the N-term region of human IMPDH2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/4/2024

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