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MAPE Antibody (C-term) Blocking Peptide

MAPE Antibody (C-term) Blocking Peptide

Item no.	ABC-BP6720b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	PRAME, MAPE, OIP4, OIP-4, Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, Preferentially expressed antigen of melanoma
Available
Primary Accession	P78395
Bio Background	MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.
Bio References	Rezvani, K., Blood 113 (10), 2245-2255 (2009)Qin, Y., Leuk. Res. 33 (3), 384-390 (2009)Neumann, E., Cancer Res. 58 (18), 4090-4095 (1998)
Gene ID	23532
Gene Name	PRAME (HGNC:9336)
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP6720b was selected from the C-term region of human MAPE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP6720b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 10/4/2024

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