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SIRT1 Antibody (Center) Blocking Peptide

SIRT1 Antibody (Center) Blocking Peptide

Manufacturer	Abcepta
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Amount	500 ug
Item no.	ABC-BP6240c
eClass 6.1	34160400
eClass 9.0	32160409
Available
Primary Accession	Q96EB6
Bio Background	SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity
Bio References	Takata, T., et al., Biochem. Biophys. Res. Commun. 301(1):250-257 (2003).Bitterman, K.J., et al., J. Biol. Chem. 277(47):45099-45107 (2002).Langley, E., et al., EMBO J. 21(10):2383-2396 (2002).Frye, R.A., Biochem. Biophys. Res. Commun. 273(2):793-798 (2000).Frye, R.A., Biochem. Biophys. Res. Commun. 260(1):273-279 (1999).
Gene ID	23411
Gene Name	SIRT1 (HGNC:14929)
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP6240c was selected from the Center region of human SIRT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP6240c-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 9/6/2024

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