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Phospho-rat TSC1(T417) Blocking Peptide

Phospho-rat TSC1(T417) Blocking Peptide

Item no.	ABC-BP3831a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	Hamartin, Tsc1, Tuberous sclerosis 1 protein homolog
Available
Primary Accession	Q9Z136
Bio Background	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Bio References	Inoue, H., et al. Biosci. Biotechnol. Biochem. 73(11):2488-2493(2009) Di Nardo, A., et al. J. Neurosci. 29(18):5926-5937(2009) Chen, P., et al. Exp. Mol. Pathol. 86(2):101-107(2009) Momose, S., et al. Biochem. Biophys. Res. Commun. 356(3):693-698(2007) Goncharova, E., et al. J. Cell Biol. 167(6):1171-1182(2004)
Gene ID	60445
Gene Name	Tsc1
Subtitle	Synthetic peptide
Other Accession	NP_068626.1
Target/Specificity	The synthetic peptide sequence is selected from aa 410-424 of RAT Tsc1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 9/6/2024

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