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Phospho-RUNX2(S465) Antibody Blocking peptide

Phospho-RUNX2(S465) Antibody Blocking peptide

Item no.	ABC-BP3559a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	RUNX2, CBFA1, OSF2, AML3, PEBP2A, Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, CBF-alpha-1, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, OSF-2
Available
Primary Accession	Q13950
Bio Background	Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Bio References	Rich, J.T., Biochem. Biophys. Res. Commun. 372 (1), 230-235 (2008)Ermakov, S., Ann. Hum. Genet. 72 (PT 4), 510-518 (2008)Endo, T., J. Clin. Endocrinol. Metab. 93 (6), 2409-2412 (2008)
Gene ID	860
Gene Name	RUNX2
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP3559a was selected from the region of human Phospho-RUNX2-pS465. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/4/2024

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