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PABPC1 Antibody (Center) Blocking Peptide

PABPC1 Antibody (Center) Blocking Peptide

Item no.	ABC-BP2920c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 5.1	34160400
ECLASS 6.1	34160400
ECLASS 8.0	32160409
ECLASS 9.0	32160409
ECLASS 10.0.1	32160409
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	PABP1, PABPC1, PAB1, PABPC2, Polyadenylate-binding protein 1, PABP-1, Poly(A)-binding protein 1
Available
Primary Accession	P11940
Bio Background	PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Bio References	Le Clerc, S., et.al., J. Infect. Dis. 200 (8), 1194-1201 (2009)
Gene ID	26986
Gene Name	PABPC1
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP2920c was selected from the Center region of human PABPC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP2920c-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 9/6/2024

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