Comparison

COPS6 Antibody (Center) Blocking Peptide

Item no. ABC-BP2869c
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products COPS6, CSN6, MOV34 homolog, COP9 signalosome complex subunit 6, hVIP, JAB1-containing signalosome subunit 6, SGN6, Signalosome subunit 6, Vpr-interacting protein, HVIP
Available
Primary Accession
Q7L5N1
Bio Background
COPS6 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Bio References
Zhao L.-J., Mukherjee S., Narayan O.J. Biol. Chem. 269:15577-15582(1994)Mahalingam S., Ayyavoo V.Proc. Natl. Acad. Sci. U.S.A. 95:3419-3424(1998)Groisman R., Polanowska J., Kuraoka I.Cell 113:357-367(2003)Hoareau Alves K., Bochard V.FEBS Lett. 527:15-21(2002)
Gene ID
10980
Gene Name
COPS6
Subtitle
Synthetic peptide
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP2869c was selected from the Center region of human COPS6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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