Item no. |
ABC-BP2784c |
Manufacturer |
Abcepta
|
Amount |
500 ug |
Category |
|
Type |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
FKBP3, Rotamase, FKBP25, FKBP-25, Peptidyl-prolyl cis-trans isomerase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-3, Immunophilin FKBP25, FK506-binding protein 3, PPIase FKBP3, Rapamycin-selective 25 kDa immunophilin |
Available |
|
Primary Accession |
Q00688 |
Bio Background |
FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
Bio References |
Yang, W.M., EMBO J. 20 (17), 4814-4825 (2001)Jin, Y.J., Proc. Natl. Acad. Sci. U.S.A. 90 (16), 7769-7773 (1993) |
Gene ID |
2287 |
Gene Name |
FKBP3 |
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence used to generate the antibody AP2784c was selected from the Center region of human FKBP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.