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NMNAT1 Blocking Peptide (C-Term)

NMNAT1 Blocking Peptide (C-Term)

Item no.	ABC-BP21921b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	NMNAT1, NMNAT, NaMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1, Nicotinate-nucleotide adenylyltransferase 1, NMN adenylyltransferase 1, 2.7.7.1, 2.7.7.18
Available
Primary Accession	Q9HAN9
Bio Background	Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.
Bio References	Schweiger M., et al.FEBS Lett. 492:95-100(2001). Emanuelli M., et al.J. Biol. Chem. 276:406-412(2001). Fernando F.S., et al.Gene 284:23-29(2002). Ota T., et al.Nat. Genet. 36:40-45(2004). Gregory S.G., et al.Nature 441:315-321(2006).
Gene ID	64802
Gene Name	NMNAT1
Subtitle	Synthetic peptide
Other Accession	Q0VD50
Target/Specificity	The synthetic peptide sequence is selected from aa 191-201 of HUMAN NMNAT1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/4/2024

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