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PROM1 Blocking Peptide (Center)

PROM1 Blocking Peptide (Center)

Item no.	ABC-BP21276c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	CD133, PROM1, Prominin-1, Antigen AC133, Prominin-like protein 1, PROML1
Available
Primary Accession	O43490
Bio Background	May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
Bio References	Miraglia S., et al.Blood 90:5013-5021(1997). Yu Y., et al.J. Biol. Chem. 277:20711-20716(2002). Lin J., et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. Wang X.Y., et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. Ota T., et al.Nat. Genet. 36:40-45(2004).
Gene ID	8842
Gene Name	PROM1
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence is selected from aa 361-375 of HUMAN PROM1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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