Item no. |
ABC-BP20965b |
Manufacturer |
Abcepta
|
Amount |
500 ug |
Category |
|
Type |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
PDX-1, PDX1, STF1, GSF, IDX-1, IPF1, STF-1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, Pancreas/duodenum homeobox protein 1 |
Available |
|
Primary Accession |
P52945 |
Bio Background |
Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell. |
Bio References |
Stoffel M., et al.Genomics 28:125-126(1995).Inoue H., et al.Diabetes 45:789-794(1996).Hiroshi I., et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.Marshak S., et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.Hara M., et al.Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. |
Gene ID |
3651 |
Gene Name |
PDX1 |
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence is selected from aa 21-35 of HUMAN PDX1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.