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PIK3R1/2 Blocking Peptide (Center)

PIK3R1/2 Blocking Peptide (Center)

Item no.	ABC-BP20768c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha
Available
Primary Accession	P27986
Bio Background	Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Bio References	Skolnik E.Y., et al.Cell 65:83-90(1991). Antonetti D.A., et al.Mol. Cell. Biol. 16:2195-2203(1996). Udelhoven M., et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. Ota T., et al.Nat. Genet. 36:40-45(2004). Totoki Y., et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Gene ID	5295
Gene Name	PIK3R1
Subtitle	Synthetic peptide
Other Accession	O00459; P23726; Q63787; P26450; P23727; Q8UUU2
Target/Specificity	The synthetic peptide sequence is selected from aa 337-350 of HUMAN PIK3R1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/4/2024

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