Bio Background |
The protein encoded by this gene is a member of theubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzymecatalyzes the covalent attachment of ubiquitin to other proteins.This protein is a part of the large multiprotein complex, which isrequired for ubiquitin-mediated degradation of cell cycle G1regulators, and for the initiation of DNA replication. [provided byRefSeq]. |
Bio References |
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Fernandez-Sanchez, M.E., et al. J. Biol. Chem. 285(23):17390-17397(2010)Choi, Y.S., et al. J. Biol. Chem. 285(23):17754-17762(2010)Wu, K., et al. Mol. Cell 37(6):784-796(2010)Kleiger, G., et al. Cell 139(5):957-968(2009) |