Bio Background |
Aquaporin 3 is a water channel protein. Aquaporins are afamily of small integral membrane proteins related to the majorintrinsic protein (MIP or AQP0). Aquaporin 3 is localized at thebasal lateral membranes of collecting duct cells in the kidney. Inaddition to its water channel function, aquaporin 3 has been foundto facilitate the transport of nonionic small solutes such as ureaand glycerol, but to a smaller degree. It has been suggested thatwater channels can be functionally heterogeneous and possess waterand solute permeation mechanisms. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kim, N.H., et al. J. Invest. Dermatol. 130(9):2231-2239(2010)Ji, C., et al. Int. J. Mol. Med. 26(2):257-263(2010)Melis, M., et al. Dis. Colon Rectum 53(6):936-943(2010)Shen, L., et al. Biomed. Pharmacother. 64(5):313-318(2010) |