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Mouse Wee1 Antibody (Center) Blocking Peptide

Mouse Wee1 Antibody (Center) Blocking Peptide

Item no.	ABC-BP19012c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	Wee1, Wee1-like protein kinase, Wee1A kinase
Available
Primary Accession	P47810
Bio Background	Wee1 may act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur (By similarity).
Bio References	Muller, M., et al. J. Cell. Sci. 123 (PT 2), 286-294 (2010) :Kim, M.J., et al. Oncol. Rep. 19(5):1323-1329(2008)Tanaka, Y., et al. Biochem. Biophys. Res. Commun. 352(1):21-28(2007)Tominaga, Y., et al. Int. J. Biol. Sci. 2(4):161-170(2006)Park, C.E., et al. Cells Tissues Organs (Print) 177(4):221-228(2004)
Gene ID	22390
Gene Name	Wee1
Subtitle	Synthetic peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 9/6/2024