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UVRAG Antibody (N-term) Blocking Peptide

UVRAG Antibody (N-term) Blocking Peptide

Item no.	ABC-BP1850a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	UVRAG, UV radiation resistance-associated gene protein, p63
Available
Primary Accession	Q9P2Y5
Bio Background	UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Bio References	Liang, C., et al. Nat. Cell Biol. 8 (7), 688-699 (2006)Ionov, Y., et al. Oncogene 23 (3), 639-645 (2004)Goi, T., et al. Surg. Today 33 (9), 702-706 (2003)Iida, A., et al. Hum. Genet. 106 (3), 277-287 (2000)Perelman, B., et al. Genomics 41 (3), 397-405 (1997)Bekri, S., et al. Cytogenet. Cell Genet. 79 (1-2), 125-131 (1997)Teitz, T., et al. Gene 87 (2), 295-298 (1990)
Gene ID	7405
Gene Name	UVRAG
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP1850a was selected from the N-term region of human Autophagy UVRAG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/4/2024

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