Bio Background |
This gene encodes a member of the galectin family.Galectins are beta-galactoside-binding animal lectins withconserved carbohydrate recognition domains. The galectins have beenimplicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widelyexpressed in tumoral tissues and seems to be involved inintegrin-like cell interactions. Alternatively spliced transcriptvariants encoding different isoforms have been identified. |
Bio References |
Cludts, S., et al. Anticancer Res. 29(12):4933-4940(2009)Cueni, L.N., et al. Exp. Cell Res. 315(10):1715-1723(2009)Yoshida, H., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 5), 512-514 (2009) :Massardo, L., et al. Lupus 18(6):539-546(2009)Savin, S., et al. Med. Oncol. 26(3):314-318(2009) |