Similar products |
PPP1R16B, ANKRD4, KIAA0823, Protein phosphatase 1 regulatory inhibitor subunit 16B, Ankyrin repeat domain-containing protein 4, CAAX box protein TIMAP, TGF-beta-inhibited membrane-associated protein, hTIMAP |
Bio Background |
The protein encoded by this gene is membrane-associatedand contains five ankyrin repeats, a proteinphosphatase-1-interacting domain, and a carboxy-terminal CAAX boxdomain. Synthesis of the encoded protein is inhibited bytransforming growth factor beta-1. The protein may bind to themembrane through its CAAX box domain and may act as a signalingmolecule through interaction with protein phosphatase-1.Alternatively spliced transcript variants encoding differentisoforms have been identified in this gene. |
Bio References |
Csortos, C., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 295 (3), L440-L450 (2008) :Kim, K., et al. Biochem. Biophys. Res. Commun. 338(3):1327-1334(2005)Homma, K., et al. J. Mol. Biol. 343(5):1207-1220(2004)Cao, W., et al. Am. J. Physiol., Cell Physiol. 283 (1), C327-C337 (2002) :Deloukas, P., et al. Nature 414(6866):865-871(2001) |