Bio Background |
LPL encodes lipoprotein lipase, which is expressed inheart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase andligand/bridging factor for receptor-mediated lipoprotein uptake.Severe mutations that cause LPL deficiency result in type Ihyperlipoproteinemia, while less extreme mutations in LPL arelinked to many disorders of lipoprotein metabolism. [provided byRefSeq]. |
Bio References |
Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010)Zabaneh, D., et al. PLoS ONE 5 (8) (2010) :Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : |