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Bad Antibody (C-term) Blocking Peptide

Bad Antibody (C-term) Blocking Peptide

Item no.	ABC-BP1314b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	BAD, Bcl2 antagonist of cell death, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, BBC6, BCL2L8, Bcl-2-like protein 8, Bcl2-associated agonist of cell death, Bcl2-L-8
Available
Primary Accession	Q92934
Bio Background	Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
Bio References	Lee, J.W., et al., Carcinogenesis 25(8):1371-1376 (2004).Zhang, B., et al., Mol. Cell. Biol. 24(14):6205-6214 (2004).Ong, C.S., et al., Oncol. Rep. 11(3):727-733 (2004).Yan, B., et al., J. Biol. Chem. 278(46):45358-45367 (2003).Taghiyev, A.F., et al., Mol. Cancer Res. 1(7):500-507 (2003).
Gene ID	572
Gene Name	BAD
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP1314b was selected from the C-term region of human Bad. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 9/6/2024

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