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Bcl-w Antibody (BH3 Domain Specific) Blocking peptide

Bcl-w Antibody (BH3 Domain Specific) Blocking peptide

Item no.	ABC-BP1305a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	BCL2L2, BCLW, KIAA0271, Bcl-2-like protein 2, Apoptosis regulator Bcl-W, Bcl2-L-2
Available
Primary Accession	Q92843
Bio Background	Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Bio References	Denisov, A.Y., et al., J. Biol. Chem. 278(23):21124-21128 (2003).Hinds, M.G., et al., EMBO J. 22(7):1497-1507 (2003).Middleton, G., et al., Development 128(3):447-457 (2001).Ross, A.J., et al., Nat. Genet. 18(3):251-256 (1998).Gibson, L., et al., Oncogene 13(4):665-675 (1996).
Gene ID	599
Gene Name	BCL2L2
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP1305a was selected from the region of human Bcl-w BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/8/2024

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