Bio Background |
The protein encoded by this gene, a member of thepeptidase C1 family, is a lysosomal cysteine proteinase that mayplay an important role in corneal physiology. This gene isexpressed in colorectal and breast carcinomas but not in normalcolon, mammary gland, or peritumoral tissues, suggesting a possiblerole for this gene in tumor processes. |
Bio References |
Puzer, L., et al. Biol. Chem. 389(2):195-200(2008)Luke, C.J., et al. Cell 130(6):1108-1119(2007)Viken, M.K., et al. Hum. Immunol. 68(9):748-755(2007)Burden, R.E., et al. Biol. Chem. 388(5):541-545(2007)Cheng, T., et al. J. Biol. Chem. 281(23):15893-15899(2006) |