Similar products |
ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1, Zinc finger FYVE domain-containing protein 1, Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1 |
Bio Background |
The FYVE domain mediates the recruitment of proteinsinvolved in membrane trafficking and cell signaling tophosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes.This gene encodes a protein which contains two zinc-binding FYVEdomains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternativelyspliced transcript variants have been found for this gene, and theyencode two isoforms with different sizes. |
Bio References |
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)Heilig, R., et al. Nature 421(6923):601-607(2003)Krugmann, S., et al. Mol. Cell 9(1):95-108(2002)Ridley, S.H., et al. J. Cell. Sci. 114 (PT 22), 3991-4000 (2001) :Cheung, P.C., et al. Biochem. J. 355 (PT 1), 113-121 (2001) : |