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PIAS1 Antibody (N-term) Blocking Peptide

PIAS1 Antibody (N-term) Blocking Peptide

Manufacturer	Abcepta
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Amount	500 ug
Item no.	ABC-BP1242a
eClass 6.1	34160400
eClass 9.0	32160409
Available
Primary Accession	O75925
Bio Background	PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
Bio References	Miyauchi, Y., et al., J. Biol. Chem. 277(51):50131-50136 (2002).Nishida, T., et al., J. Biol. Chem. 277(44):41311-41317 (2002).Tan, J.A., et al., J. Biol. Chem. 277(19):16993-17001 (2002).Megidish, T., et al., J. Biol. Chem. 277(10):8255-8259 (2002).Liu, B., et al., J. Biol. Chem. 276(39):36624-36631 (2001).
Gene ID	8554
Gene Name	PIAS1
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP1242a was selected from the N-term region of human PIAS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP1242a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 9/6/2024

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