Genuin Biotechnologies

GenuIN Biotech LLC, founded in March 2018 in Virginia, USA, focuses on providing validated gene-silencing tools and high-quality antibodies for biomedical research. Their core technology, the ShGE™ gene silencing platform, employs lentivirus-mediated short hairpin RNA (shRNA) to knock down gene expression at the mRNA level, enabling high-throughput and cost-effective gene silencing.

Genuin Biotechnologies also offers products like KD/KO-validated antibodies, lentiviruses, and cell lysates, and services such as antibody validation, lentivirus construction, and customized monoclonal antibodies. Their technology aims to enhance the reproducibility of research, accelerate disease diagnosis, and support cutting-edge studies in fields like epigenetics and cancer.

Their most popular products are FadeStop™, amounting medium that is specially formulated to prolong the intensity of the fluorescence used in immunocytochemical and immunohistochemical staining. This product can protect the fluorescent dyes from photobleaching for at least four months if the slides are stored at -20°C.

Another product is the IntactProtein™ Cell-Tissue Lysis Kit. The all-in-one formula offers a ready-to-use solution for protein extraction that eliminates the need for protease inhibitors, other enzyme inhibitors, or sonication. Furthermore, it preserves post-translational modifications (PTMs) like phosphorylation, glycosylation, and ubiquitination, providing assurance of no protein loss. Its versatile performance makes it ideal for both mammalian cells and tissues.

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