« Back
Home /
Partner: Creative Biolabs |Hölzel Diagnostika

Creative Biolabs

Creative Biolabs – Antibody manufacturing and development

Creative Biolabs Inc. was founded in New York, USA by experienced scientists concerned with the treatment and prevention of difficult-to-treat diseases such as cancer. Today the respected company has a worldwide network and serves customers around the globe. Creative Biolabs is one of the leading custom service providers with extensive experience in various areas of antibody production and development.

Our partner's service portfolio includes the production of monoclonal antibodies from mice and rats using hybridoma technology, as well as the production of monoclonal antibodies from numerous other species using a variety of antibody library technologies (phage display, bacteria display, and yeast display). The professional implementation of a thorough humanization and maturation of antibodies using phage display and DNA mutagenesis approaches is also one of the particular strengths of Creative Biolabs.

The phage display technology relies on technical bacteriophages to display molecules (e.g. proteins and peptides) on their surface. For this purpose, the gene coding for the target molecule is inserted into the gene of the phage coat protein, which results in target molecule expression. It is fused with the coated protein of the bacteriophage particles. The phage display library is constructed by assembling millions of genetically engineered phage that can be used for further screening and selection. This platform can help mimic natural molecules in the cellular process and recognize their interaction with other molecules.

Creative Biolabs is a leading global provider of phage display library technology. The first-class premade Phage Display Antibody Libraries for humans, mice or individual domains have a high capacity and diversity. You can derive highly specific antibodies whose affinity is in the range from 10 pM to 10 nM. The ready-made screening of human antibodies is a powerful tool for various therapeutic and diagnostic antibody development programs. Numerous mentions in well-known references confirm Creative Biolabs product quality, various antibody candidates have already been used in preclinical or clinical studies. In addition to providing industry-leading design services for custom phage display libraries, Creative Biolabs also offers dozens of immunized human antibody libraries with good sensitivity and specificity. These immunized Fab and scFv antibody libraries form a valuable experimental basis for the further investigation of B-cell lymphoma and can potentially also contribute to improving the therapy of many diseases.