3CR Bioscience
About 3CR Bioscience
Founded in 2017, 3CR Bioscience is based in the United Kingdom, near Harlow.
Since its establishment, the company has had one goal: to sell high-quality laboratory reagents at affordable and competitively fair prices. It is precisely because of this that researchers can generate more data and advance understanding in science.
From the beginning, 3CR Bioscience's team has a long experience in relevant areas of the industry, through competent staff. More specifically, the knowledge and experience is also reflected in research and development, as well as manufacturing and quality control.
What is the PACETM technology?
The abbreviation PACETM means PCR Allele Competitive Extension, which consequently corresponds to a universal PCR master mix for genotyping. In fact, PACE is specifically designed for use with allele-specific assays (e.g. ASPTM, Amplifluor®, etc.)
The PACETM Genotyping Master Mix product is 2X concentrated, further the product contains a ROX normalization dye. Furthermore, the dye is available in three concentrations: high concentration of 500 nM, standard concentration of 150 nM or low concentration which is 25 nM.
In contrast, the PACETM Genotyping Master Mix has an improvement against unspecific amplification compared to other mixes. In addition, only this master mix is needed, regardless of reaction volume, which reduces costs.
Discover some of 3CR Bioscience's products based on PACETM technology below.
Name | Art. No. |
---|---|
PACETM Genotyping Master Mix | 3CR-001-0001 |
PACETM 2.0 Genotyping Master Mix | 3CR-003-0008 |
PACE-IRTM Genotyping Master Mix | 3CR-004-0001 |
The ProbeSureTM Genotyping Master Mix
The ProbeSureTM Genotyping Master Mix is also a PCR reagent for genotyping application, but with application in hydrolysis probe based assays. For this reason, it is not to be used as a general PCR Master Mix or for or HRM applications.
Rather, this Master Mix is specifically designed for endpoint fluorescent detection of single nucleotide polymorphisms (SNPs) and insertions/deletions (indels). In addition, the master mix provides accurate genotyping clusters and high hit rates for accurate and reproducible allele discrimination.
All components necessary to perform the reaction (except DNA and primers/probes) are included. Furthermore, the Master Mix is supplied 2 times concentrated. It is formulated with dTTP as this increases reaction sensitivity and efficiency compared to mixtures with dUTP.
Name | Art. No. |
---|---|
ProbeSureTM Genotyping Master Mix | 3CR-002-0001 |
ProbeSureTM Multiplex Master Mix | 3CR-006-0005 |
ProbeSure-IRTM Genotyping Master Mix | 3CR-005-0007 |
We are very happy about a successful collaboration with our partner company 3CR Bioscience!
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