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RAB7A cDNA

RAB7A cDNA

Item no.	NKM-ATGD0205-10ug
Manufacturer	NKMAX
Amount	10ug
Category	Neuroscience Targets for Rodent Neurosciences Cell Biology Cytoskeleton Nucleic Acids DNA cDNA small GTPases Rab Subfamily
Type	cDNA
Specific against	other
Sequence	ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTT
Vector	pATGen (puc19 - derived cloning vector)
NCBI	NP_004628.4
ECLASS 10.1	32160414
ECLASS 11.0	32160414
UNSPSC	41105324
Alias	PRO2706, RAB7
Available
Antigen Species	Human
Chromosome Location	3q21.3
DNA size	624bp
Description	RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. RAB7A encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded RAB7A is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in RAB7A have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Formulation	Lyophilized
Gene Category	Signal Transduction
OMIM reference Number	602298
Preparation before usage	1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
RNA Reference Number	NM_004637.5
Storage	Store the plasmid at -20C.
Translation Sequence	MTSRKKVLLK VIILGDSGVG KTSLMNQYVN KKFSNQYKAT IGADFLTKEV MVDDRLVTMQIWDTAGQERF QSLGVAFYRG ADCCVLVFDV TAPNTFKTLD SWRDEFLIQA SPRDPENFPFVVLGNKIDLE NRQVATKRAQ AWCYSKNNIP YFETSAKEAI NVEQAFQTIA RNALKQETEVELYNEFPEPI KLDKNDRAKA SAESCSC
Vector description	This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10ug

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Delivery expected until 1/31/2025

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