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Phospholipase A2 P00630 Bee Venom Protein Recombinant ( Phospholipase A2 )

Phospholipase A2 P00630 Bee Venom Protein Recombinant ( Phospholipase A2 )

Item no.	PT_41752_500ug
Manufacturer	Novateinbio
Amount	500 ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Cardiovascular Research Thrombosis & Hemostasis Enzymes Fatty Acid Catabolism
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Phospholipase A2 P00630 Bee Venom Protein Recombinant ( Phospholipase A2 )
Similar products	Phospholipase A2 P00630 Bee Venom Protein Recombinant ( Phospholipase A2 )
Available
Description	The E.Coli derived recombinant protein contains phospholipase P00630 bee venom protein epitopes, 26-162 amino acids.
Storage/Stability	Phospholipase A2 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity	Protein is > 90% pure as determined by 10% SDS-PAGE.
Form	20mM Tris-HCl, pH 7.2, 1.5M urea and 50% glycerol.
Protein Background	Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 1416-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
Expression host	Escherichia Coli.
Manufacturers Category	Signaling Pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 9/13/2024

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