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Description: ABT-724 isa novel, potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM. It was developed as a possible drug for the treatment of erectile dysfunction. It could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.
References:
1. Activationof dopamine D4 receptors by ABT-724 induces penile erection in rats.Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6758-63.
2. Sanna F, Contini A, Melis MR, Argiolas A. Role of dopamine D4 receptors in copulatory behavior: Studies with selective D4 agonists and antagonists in male rats. Pharmacol Biochem Behav. 2015 Oct; 137:110-8.
Related CAS #: 70006-24-5 (free base) 587870-77-7 (HCl)
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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