abacavir

Description: Abacavir (formerly also known as ABC, or 1592U89; trade names: Ziagen; Epzicom) is a commonly used nucleoside analogue of the NRTI class with potent antiviral activity against HIV-1. Abacavir is a widely used antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse transcriptase inhibitor (NRTI) type. Viral strains that are resistant to zidovudine (AZT) or lamivudine (3TC) are generally, but not always, sensitive to abacavir. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

References: Lancet. 2002 Mar 2; 359(9308):727-32; N Engl J Med. 2008 Feb 7; 358(6):568-79.

Related CAS#:136470-78-5 (free base); 136777-48-5 (HCl); 168146-84-7 (succinate); 1446418-48-9 (acetate); 384380-52-3 (Abacavir carboxylate); 188062-50-2 (sulfate)