bam-7

Item no.	V8454-5mg
Manufacturer	InvivoChem LLC
CASRN	331244-89-4
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	331244-89-4
Available
Description	InvivoChem Cat #:V8454CAS #:331244-89-4Purity >=98% Description: BAM 7 is a Bax activator (EC50 = 3.3 uM). BCL-2 family proteins are key regulators of the apoptotic pathway. Antiapoptotic members sequester the BCL-2 homology 3 (BH3) death domains of proapoptotic members such as BAX to maintain cell survival. The antiapoptotic BH3-binding groove has been successfully targeted to reactivate apoptosis in cancer. References: Gavathiotis E, Reyna DE, Bellairs JA, Leshchiner ES, Walensky LD. Direct andselective small-molecule activation of proapoptotic BAX. Nat Chem Biol. 2012Jul; 8(7):639-45. doi: 10.1038/nchembio.995. Epub 2012 May 27. PubMed PMID:22634637; PubMed Central PMCID: PMC3617124.

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Amount: 5mg

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Delivery expected until 9/6/2024