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Description: Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Acyline inhibits basal and GnRH-stimulated serum testosterone concentrations in male dogs. Acyline prevented ovulation, but did not affect ovarian follicular development or gestational corpora lutea in the domestic cat. A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men.
References: Zysling DA, Park SU, McMillan EL, Place NJ. Photoperiod-gonadotropin mismatches induced by treatment with acyline or FSH in Siberian hamsters: impacts on ovarian structure and function. Reproduction. 2012 Nov; 144(5):603-16. doi: 10.1530/REP-12-0155. Epub 2012 Aug 30. PubMed PMID: 22936286.
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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Delivery expected until 9/6/2024
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