allo-2

Item no.	V5681-5mg
Manufacturer	InvivoChem LLC
CASRN	1357350-60-7
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5681CAS #:1357350-60-7Purity >=98% Description: ALLO-2 is a novel and potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM. References: Smallmolecule antagonists in distinct binding modes inhibit drug-resistantmutant of smoothened. Chem Biol. 2011 Apr 22; 18(4):432-7.; New frontiers in pediatric Allo-SCT. Bone Marrow Transplant. 2014 Sep; 49(9):1139-45. doi: 10.1038/bmt.2014.89. Epub 2014 May 12. Review. PubMed PMID: 24820213; PubMed Central PMCID: PMC4439009.

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