diquafosol-tetrasodium

InvivoChem Cat #:V5253CAS #:211427-08-6Purity >=98%

Description: Diquafosol tetrasodium (Diquas; INS-365) is a novel and potent P2Y2 purinoceptor agonist that stimulates fluid and mucin secretion on the ocular surface, and is used as a topical treatment of dry eye disease.

References: Invest Ophthalmol Vis Sci. 2001 Jan; 42(1):96-100.

Related CAS: 59985-21-6 (free base); 147780-24-3 (Hyaluronate free acid); 9067-32-7 (Hyaluronate sodium); 90098-04-7 ( Rebamipide; Proamipide; Mucosta)

-20C for 3 years in powder form

Synonym: INS-365; DE-089; KPY-998; INS 365; DE 089; KPY 998; INS365; DE089; KPY998; Diquas
Chemical Name: Uridine 5'-(pentahydrogen tetraphosphate), P'''-5'ester with uridine, tetrasodium salt
InChi Key: OWTGMPPCCUSXIP-CNJHCLCISA-J
InChi Code: InChI=1S/C18H26N4O23P4.4Na/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31, 32)43-48(35, 36)45-49(37, 38)44-47(33, 34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30; ; ; ; /h1-4, 7-8, 11-16, 25-28H, 5-6H2, (H, 31, 32)(H, 33, 34)(H, 35, 36)(H, 37, 38)(H, 19, 23, 29)(H, 20, 24, 30); ; ; ; /q; 4*+1/p-4/t7-, 8-, 11-, 12-, 13-, 14-, 15-, 16+; ; ; ; /m1..../s1
SMILES Code: O[CH]([CH]([CH](COP(OP(OP(OP(OC[CH]1[CH]([CH](O)[CH](O1)N2C(NC(C=C2)=O)=O)O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)O3)O)[CH]3N(C(N4)=O)C=CC4=O.[Na+].[Na+].[Na+].[Na+]