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vadadustat

vadadustat

Item no.	V5246-250mg
Manufacturer	InvivoChem LLC
CASRN	1000025-07-9
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5246CAS #:1000025-07-9 Purity >=98% Description: Vadadustat (PG-1016548; AKB-6548) is a titratable and orally bioavailable hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor that induces endogenous erythropoietin synthesis and enhances iron mobilization. It is under development for the treatment of anemia. Current treatment of anemia in chronic kidney disease (CKD) with erythropoiesis-stimulating agents can lead to substantial hemoglobin oscillations above target range and high levels of circulating erythropoietin. References: Kidney Int. 2016 Nov; 90(5):1115-1122.
	Name: Vadadustat CAS#: 1000025-07-9 Chemical Formula: C14H11ClN2O4 Exact Mass: 306.0407 Molecular Weight: 306.7 Elemental Analysis: C, 54.83; H, 3.62; Cl, 11.56; N, 9.13; O, 20.87
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: AKB-6548; AKB 6548; AKB6548; PG-1016548; PG 1016548; PG1016548; B-506; B506; Vadadustat Chemical Name: (5-(3-chlorophenyl)-3-hydroxypicolinoyl)glycine InChi Key: JGRXMPYUTJLTKT-UHFFFAOYSA-N InChi Code: InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6, 18H, 7H2, (H, 17, 21)(H, 19, 20) SMILES Code: O=C(O)CNC(C1=NC=C(C2=CC=CC(Cl)=C2)C=C1O)=O

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Amount: 250mg

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