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bohemine

bohemine

Item no.	V5209-250mg
Manufacturer	InvivoChem LLC
CASRN	189232-42-6
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5209CAS #:189232-42-6Purity >=98% Description: Bohemine, structurally similar to Olomoucine and Roscovitine, is a novel, potent, selective, and cell-permeable cyclin-dependent kinase (CDK) with IC50s of 4.6, 83, and 2.7 uM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 uM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities. B References: Clin Cancer Res. 2005 Jul 1; 11(13):4875-87.
	Name: Bohemine CAS#: 189232-42-6 Chemical Formula: C18H24N6O Exact Mass: 340.20116 Molecular Weight: 340.43 Elemental Analysis: C, 63.51; H, 7.11; N, 24.69; O, 4.70
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Chemical Name: 3-((6-(benzylamino)-9-isopropyl-9H-purin-2-yl)amino)propan-1-ol InChi Key: OPQGFIAVPSXOBO-UHFFFAOYSA-N InChi Code: InChI=1S/C18H24N6O/c1-13(2)24-12-21-15-16(20-11-14-7-4-3-5-8-14)22-18(23-17(15)24)19-9-6-10-25/h3-5, 7-8, 12-13, 25H, 6, 9-11H2, 1-2H3, (H2, 19, 20, 22, 23) SMILES Code: CC(N1C=NC2=C1N=C(NCCCO)N=C2NCC3=CC=CC=C3)C

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Amount: 250mg

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