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lersivirine

lersivirine

Item no.	V5189-500mg
Manufacturer	InvivoChem LLC
CASRN	473921-12-9
Amount	500mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5189CAS #:473921-12-9Purity >=98% Description: Lersivirine (formerly UK-453061) is a novel next-generation and potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 119 nM and a unique resistance profile. It exhibits potent antiretroviral activity against wild-type human immunodeficiency virus and clinically relevant NNRTI-resistant strains. Lersivirine was under development for HIV infection therapy. It binds reverse transcriptase in a distinct way leading to a unique resistance profile. In February 2013, ViiV Healthcare announced the development of lersivirine was disconinued. References: Bioorg Med Chem Lett. 2009 Oct 15; 19(20):5857-60. Related CAS: 147362-57-0 (Loviride); 16837-52-8 (Oxymatrine?
	Name: Lersivirine CAS#: 473921-12-9 Chemical Formula: C17H18N4O2 Exact Mass: 310.143 Molecular Weight: 310.357 Elemental Analysis: C, 65.79; H, 5.85; N, 18.05; O, 10.31
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: UK-453061; UK453061; UK 453061; UK-453, 061; UK453, 061; UK 453, 061 Chemical Name: 5-((3, 5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl)oxy)isophthalonitrile InChi Key: MCPUZZJBAHRIPO-UHFFFAOYSA-N InChi Code: InChI=1S/C17H18N4O2/c1-3-15-17(16(4-2)21(20-15)5-6-22)23-14-8-12(10-18)7-13(9-14)11-19/h7-9, 22H, 3-6H2, 1-2H3 SMILES Code: N#CC1=CC(OC2=C(CC)N(CCO)N=C2CC)=CC(C#N)=C1

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Amount: 500mg

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