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vatiquinone

vatiquinone

Item no.	V5050-25mg
Manufacturer	InvivoChem LLC
CASRN	1213269-98-7
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5050CAS #:1213269-98-7Purity >=98% Description: Vatiquinone (formerly also known as EPI-743), a para-benzoquinone analog being developed for inherited mitochondrial diseases, is a novel, potent and orally bioavailable cellular oxidative stress protectant, which could be potentially used to treat mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, optimizing metabolic control, enhancing the expression of genetic elements critical for cellular management of oxidative stress, and acting at the mitochondria to regulate electron transport. Leigh syndrome is a mitochondrial disease caused by respiratory chain deficiency, and there are no proven effective therapies. EPI-743 is a potent cellular oxidative stress protectant and results of clinical trials for mitochondrial diseases are accumulating. References: Brain Dev. 2018 Feb; 40(2):145-149.
	Name: Vatiquinone CAS#: 1213269-98-7 Chemical Formula: C29H44O3 Exact Mass: 440.329 Molecular Weight: 440.668 Elemental Analysis: C, 79.04; H, 10.06; O, 10.89
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: EPI743; EPI-743; EPI 743; alpha-Tocotrienol quinone. ATQ3; ATQ-3 Chemical Name: 2-((R, 6E, 10E)-3-hydroxy-3, 7, 11, 15-tetramethylhexadeca-6, 10, 14-trien-1-yl)-3, 5, 6-trimethylcyclohexa-2, 5-diene-1, 4-dione InChi Key: LNOVHERIIMJMDG-XZXLULOTSA-N InChi Code: InChI=1S/C29H44O3/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8, 32)19-17-26-25(7)27(30)23(5)24(6)28(26)31/h12, 14, 16, 32H, 9-11, 13, 15, 17-19H2, 1-8H3/b21-14+, 22-16+/t29-/m1/s1 SMILES Code: O=C1C(CC[C](C)(O)CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(C)C(C(C)=C1C)=O

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Amount: 25mg

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Delivery expected until 9/6/2024